New insights into keloid pathogenesis: biomarker potential for CDK7 and DDB2
Our findings demonstrate that CDK7 and DDB2 are promising biomarkers for diagnostic and potential therapeutic targets in keloid, providing novel insights into its pathogenesis and offering promising druggable targets.
Authors
- Lujia Mao
- Lusheng Xu
- Xiaoxiang Wang
- Ronghua Yang (ORCID: https://orcid.org/0000-0002-9685-7003)
- Yuting Zhang (ORCID: https://orcid.org/0000-0002-6460-6779)
- Weiqiang Zhang (ORCID: https://orcid.org/0000-0002-7278-5033)
- Fujun Wang (ORCID: https://orcid.org/0000-0002-2851-6709)
Institutions
- Sun Yat-sen University (CN)
- Guangdong Medical College (CN)
- First People's Hospital of Foshan (CN)
- Guangzhou First People's Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Qiqihar Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-11-19
- DOI
- https://doi.org/10.3389/fcell.2025.1718189
- Primary Topic
- Dermatologic Treatments and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Basic and Applied Basic Research Foundation of Guangdong Province