Exosomes derived from Panax notoginseng promote osteogenic differentiation of rBMSCs via the PI3K/AKT signaling pathway
Panax notoginseng exosomes promote osteogenic differentiation of rBMSCs by activating the PI3K/AKT pathway, providing experimental evidence and theoretical support for the application of herbal exosomes in bone tissue engineering and osteoporosis treatment.
Authors
- Lintao Zhang (ORCID: https://orcid.org/0000-0003-0523-8950)
- Hua Guo (ORCID: https://orcid.org/0000-0001-5433-0759)
- Nan Wu (ORCID: https://orcid.org/0000-0002-8627-535X)
Institutions
- Wuhan University (CN)
- Fifth Hospital In Wuhan (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-11-19
- DOI
- https://doi.org/10.3389/fphar.2025.1682548
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00