Feasibility of DNA and RNA preservation from EBUS-TBNA supernatant for molecular profiling in non-small cell lung cancer
Sp obtained from EBUS-TBNA is a rich source of tumour DNA and RNA, with high feasibility for NGS. There is strong concordance of NGS results between Cp and Sp, supporting Sp as a complementary/alternative source for molecular profiling in NSCLC, potentially reducing the need for additional biopsies.
Authors
- Luís Vaz Rodrigues (ORCID: https://orcid.org/0000-0001-5929-6078)
- Rosa Cordovilla (ORCID: https://orcid.org/0000-0001-8907-1072)
- Ana Alarcão (ORCID: https://orcid.org/0000-0002-3783-2404)
- Ana Filipa Ladeirinha
- Luís Taborda‐Barata (ORCID: https://orcid.org/0000-0001-6649-8890)
- Vítor Sousa (ORCID: https://orcid.org/0000-0003-3219-1078)
- Joana Oliveira (ORCID: https://orcid.org/0000-0001-8723-670X)
Institutions
- University of Beira Interior (PT)
- Universidad de Salamanca (ES)
- Instituto Português de Oncologia Francisco Gentil (PT)
- Instituto de Investigación Biomédica de Salamanca (ES)
- Instituto Português de Oncologia de Coimbra Francisco Gentil (PT)
- Escola Superior de Enfermagem de Coimbra (PT)
- University of Coimbra (PT)
Publication Details
- Journal
- Pulmonology
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1080/25310429.2025.2588834
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 0.00