Population Pharmacokinetics of Propofol in Critically Ill Patients with and Without Extracorporeal Membrane Oxygenation

Our popPK analysis shows that propofol PK does not differ between critically ill patients with and without ECMO and confirms a high PK variability in this population.

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Publication Details

Journal
Clinical Pharmacokinetics
Published
2025-11-20
DOI
https://doi.org/10.1007/s40262-025-01585-2
Primary Topic
Anesthesia and Sedative Agents
Type
article
Field-Weighted Citation Impact
0.00
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article

Population Pharmacokinetics of Propofol in Critically Ill Patients with and Without Extracorporeal Membrane Oxygenation

Laurent Arthur Decosterd, David Haefliger, Antoine Schneider, Françoise Livio et al.
Clinical Pharmacokinetics
Anesthesia and Sedative Agents
article

Population Pharmacokinetics of Propofol in Critically Ill Patients with and Without Extracorporeal Membrane Oxygenation

Laurent Arthur Decosterd, David Haefliger, Antoine Schneider, Françoise Livio, Monia Guidi, Benjamin Assouline, Thomas Mercier, Raphaël Giraud, Thierry Buclin, Stéphane Bertin
article en

Abstract

Our popPK analysis shows that propofol PK does not differ between critically ill patients with and without ECMO and confirms a high PK variability in this population.

Clinical PharmacokineticsVol. 65(2)
Centre Hospitalier Universitaire Vaudois (CH), University Hospital of Geneva (CH), Geneva College (US), University of Lausanne (CH)
Openalex Percentile: Top 47%
Anesthesia and Sedative Agents
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Population Pharmacokinetics of Propofol in Critically Ill Patients with and Without Extracorporeal Membrane Oxygenation — Laurent Arthur Decosterd, David Haefliger, et al. · Clinical Pharmacokinetics (2025) | TGRS Research Map | TGRS