Assessing the implementation determinants of antimicrobial stewardship programmes in sub-Saharan Africa through the complexity lens. A CFIR-guided systematic review
AMS implementation in SSA is constrained by systemic, infrastructural, and educational challenges. Strengthening leadership, surveillance systems, healthcare worker training, and the development of context-specific AMS protocols are essential. Effective implementation will require tailored strategies grounded in local realities and supported by strong governance and sustainable funding mechanisms.
Authors
- Thomas Nyirenda (ORCID: https://orcid.org/0000-0003-4727-7130)
- Steward Mudenda (ORCID: https://orcid.org/0000-0003-1692-8981)
- Gracian Harawa (ORCID: https://orcid.org/0000-0002-8568-7491)
- Cheongho Han (ORCID: https://orcid.org/0000-0002-2641-9964)
- Tumaini Makole (ORCID: https://orcid.org/0009-0007-7258-4403)
- Ju Hye Chung (ORCID: https://orcid.org/0000-0001-9543-7181)
- Adriano Focus Lubanga (ORCID: https://orcid.org/0000-0002-5491-5412)
- Akim Nelson Bwanali (ORCID: https://orcid.org/0009-0005-2070-0041)
- Gertrude Diana Chumbi
- Stuart Ssebibubbu
- Thandizo Kapatsa
- George Lee (ORCID: https://orcid.org/0000-0003-1614-9363)
- Seongwon Chung
- Dowon Chung
- Chitemwa Moyo
- Abdisalam Yusuf Ali
- Sung‐Jae Chung
- Gillian Mwale
- Cynthia Chitule
- Vitumbiko Mkandawire
- Abigail Masi
- Victoria Hwang
- Leonard Naphazi Kambewa
Institutions
- Mount Kenya University (KE)
- Stellenbosch University (ZA)
- Inova Fairfax Hospital (US)
- University of Zambia (ZM)
- Public Health Institute of Malawi (MW)
- Ministry of Health (MW)
- National Agricultural Research Institute (UG)
- Queen Elizabeth Central Hospital (MW)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-11-19
- DOI
- https://doi.org/10.3389/fmicb.2025.1660778
- Citations
- 1
- Primary Topic
- Antibiotic Use and Resistance
- Type
- article
- Field-Weighted Citation Impact
- 1.26