Case Report: Severe kidney involvement in a case of very early onset inflammatory bowel disease
Vedolizumab-related acute TIN is a potentially severe complication, rarely described in adult patients. We report the first case of VEO-IBD with a probable vedolizumab-related acute TIN treated with corticosteroids, with a good response and maintenance of vedolizumab. Persisting sterile leukocyturia could represent an early sign.
Authors
- Andrea Angeletti (ORCID: https://orcid.org/0000-0002-6121-5326)
- Enrico Drago (ORCID: https://orcid.org/0000-0002-0836-3610)
- Sara Signa (ORCID: https://orcid.org/0000-0002-9083-1726)
- Roberta Carfora
- Laura Puzone
- Gabriele Gaggero (ORCID: https://orcid.org/0000-0001-9098-563X)
- Barbara Cafferata (ORCID: https://orcid.org/0009-0005-4436-4660)
- Edoardo La Porta (ORCID: https://orcid.org/0000-0003-2368-1139)
- Valerio Gaetano Vellone (ORCID: https://orcid.org/0000-0002-5107-1584)
- Serena Arrigo (ORCID: https://orcid.org/0000-0002-5564-7018)
- Paolo Gandullia (ORCID: https://orcid.org/0000-0002-7901-4995)
Institutions
- Istituto Giannina Gaslini (IT)
- University of Genoa (IT)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-19
- DOI
- https://doi.org/10.3389/fimmu.2025.1684476
- Citations
- 1
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 1.82