National Breast Cancer Surgery Snapshot Study: Breast Cancer Surgery after Neoadjuvant Systemic Therapy in Primary Breast Cancer (MANS Study)
In the Netherlands the main reasons for NST were subtype (triple negative, HER2+) and axillary down staging. Additional reasons for NST focused more on down staging to convert to BCS and improve cosmetic outcomes. Real time data showed that NST lead to very high conversion rates from mastectomy to BCS as well as high rates of omission of ALND after NST.
Authors
- Petrousjka van den Tol
- José H. Volders (ORCID: https://orcid.org/0000-0002-9190-4579)
- Roza C.M. Opperman (ORCID: https://orcid.org/0000-0002-7279-0940)
- Florian Haring
- P.E.R. Spronk (ORCID: https://orcid.org/0000-0003-1551-8390)
- Marie‐Jeanne Vrancken Peeters
- Gaelle Kramer
Institutions
- The Netherlands Cancer Institute (NL)
- Diakonessenhuis hospital (NL)
Publication Details
- Journal
- Clinical Breast Cancer
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.clbc.2025.10.019
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00