Gestational exposure to PM2.5 impaired cardiac development through ANGPTL4-mediated mitochondrial metabolic dysfunction
These findings suggested that PM<sub>2.5</sub> may impair cardiac development through ANGPTL4-mediated mitochondrial dysfunction, which provided a mechanistic basis for further investigation and prevention of PM<sub>2.5</sub>-related birth defects.
Authors
- Junchao Duan (ORCID: https://orcid.org/0000-0002-1455-304X)
- Li Tian (ORCID: https://orcid.org/0000-0001-7359-7571)
- Ruiyang Ding (ORCID: https://orcid.org/0000-0003-2464-5594)
- Shiqian Liu (ORCID: https://orcid.org/0000-0003-4212-3618)
- Zhiru Liu
- Liang Chen (ORCID: https://orcid.org/0000-0003-0554-2733)
- Ruixia Liu (ORCID: https://orcid.org/0000-0001-5835-4424)
- Z. Xiong (ORCID: https://orcid.org/0009-0001-6220-4063)
- Chenghong Yin
- Jianong Lv
- Zhiwei Sun (ORCID: https://orcid.org/0009-0008-1745-243X)
Institutions
- Capital Medical University (CN)
- Beijing Obstetrics and Gynecology Hospital (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1016/j.jare.2025.11.022
- Primary Topic
- Lipid metabolism and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00