Peptide IRW upregulates ACE2 in spontaneously hypertensive rats via dopamine/D1R signaling pathway
IRW-driven ACE2 upregulation in vivo relies on the dopamine/D1R signaling pathway, highlighting the therapeutic potential of this pathway for ACE2-related conditions.
Authors
- Le Luo Guan (ORCID: https://orcid.org/0000-0002-8420-4371)
- Z. Wang (ORCID: https://orcid.org/0000-0001-9397-9163)
- Jian Wu (ORCID: https://orcid.org/0000-0002-3394-1507)
Institutions
- University of British Columbia (CA)
- University of Alberta (CA)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1016/j.jare.2025.11.020
- Citations
- 2
- Primary Topic
- Renin-Angiotensin System Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.78