Development of a single-cell derived MDSCs signature score for prognostic risk stratification and therapeutic decision guidance in breast cancer
This investigation marks the initial systematic characterization of a new MDSCs gene signature in breast cancer, alongside the establishment of an MDSCs-associated marker scoring framework with multi-aspect clinical translation capability, thereby linking MDSCs fundamental biology to precision oncology in this cancer type.
Authors
- Binbin Li (ORCID: https://orcid.org/0000-0002-8572-8003)
- Jinbao Yin
- Hui Xiong
- Junyu Gan
- Lan Liang (ORCID: https://orcid.org/0009-0006-1004-5714)
Institutions
- Guangdong Medical College (CN)
- Dongguan University of Technology (CN)
Publication Details
- Journal
- Translational Oncology
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.tranon.2025.102605
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.00