Drynachromoside A from <i>Drynaria fortunei</i> attenuates oxidative stress and fibrosis of diabetic nephropathy via activating Nrf2 <i>in vitro</i> and <i>in vivo</i>
DCSA identified in <i>Drynaria fortunei</i> is a Keap1-dependent Nrf2 activator with the potential to attenuate DN. This investigation could provide novel insights into the discovery of Nrf2 activators and new therapeutic approaches for DN.
Authors
- Ruiqing Wu
- Dan Du (ORCID: https://orcid.org/0000-0001-8762-1499)
- Huankai Yao (ORCID: https://orcid.org/0000-0002-6316-3523)
- Yan Li (ORCID: https://orcid.org/0000-0001-5723-6936)
- Jindong Li (ORCID: https://orcid.org/0000-0001-9050-2896)
- Fengwei Ai
Institutions
- Xuzhou Medical College (CN)
- Nantong University (CN)
- The Affiliated Taizhou People's Hospital of Nanjing Medical University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Redox Report
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1080/13510002.2025.2591473
- Primary Topic
- Genomics, phytochemicals, and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 0.00