Transcatheter Aortic Valve Replacement for Severe Native Aortic Valve Regurgitation: A Multicenter and International Registry
•Transcatheter aortic valve replacement for native aortic valve regurgitation is feasible but with modest technical success (79.8%).•Balloon-expandable valve use is linked to lower 30-day major adverse cardiac events versus self-expanding valve in high-risk patients.•Long-term outcomes driven by patient risk, not valve type.•Dedicated native aortic regurgitation systems still needed to improve procedural safety.
Authors
- Timothy Byrne (ORCID: https://orcid.org/0000-0002-2550-9335)
- Sant Kumar (ORCID: https://orcid.org/0000-0001-5294-3682)
- Ashish Pershad (ORCID: https://orcid.org/0000-0002-6424-4341)
- Soundos Moualla
- David Elison (ORCID: https://orcid.org/0000-0002-9367-2724)
- Simone Biscaglia (ORCID: https://orcid.org/0000-0001-6074-2370)
- Ahmad Jabri (ORCID: https://orcid.org/0000-0003-0161-2378)
- Ei Ei Thwe (ORCID: https://orcid.org/0009-0001-9163-3756)
- Hursh Naik
- Amr E. Abbas (ORCID: https://orcid.org/0000-0002-7316-4247)
- Ivan Hanson (ORCID: https://orcid.org/0000-0002-0481-9764)
- Nezar Falluji
- Jacopo Farina (ORCID: https://orcid.org/0009-0003-9198-2600)
- Francesco Saia (ORCID: https://orcid.org/0000-0001-9969-2649)
- Carlo Tumscitz (ORCID: https://orcid.org/0000-0003-0811-5411)
- Pedro Villablanca (ORCID: https://orcid.org/0000-0002-6266-9637)
Institutions
- Creighton University (US)
- St. Joseph's Hospital and Medical Center (US)
- University of Washington (US)
- Dignity Health (US)
- Henry Ford Hospital (US)
- Azienda USL di Bologna (IT)
- Arcispedale Sant'Anna (IT)
- Beaumont Hospital, Royal Oak (US)
- Regional Medical Center (US)
- Phoenix Indian Medical Center (US)
Publication Details
- Journal
- Structural Heart
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.shj.2025.100762
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00