Impact of initial hematocrit levels during direct procurement and perfusion on the likelihood of primary graft dysfunction in donation after circulatory death heart transplantation

Higher perfusate HCT was not associated with reduced PGD and may be linked to increased postoperative support requirements. These findings raise important questions about optimal HCT levels for ex vivo perfusion and warrant further prospective investigation.

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Publication Details

Journal
JHLT Open
Published
2025-11-20
DOI
https://doi.org/10.1016/j.jhlto.2025.100442
Primary Topic
Transplantation: Methods and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Impact of initial hematocrit levels during direct procurement and perfusion on the likelihood of primary graft dysfunction in donation after circulatory death heart transplantation

Esther Odekunle, George Olverson, Ioannis Mastoris, S. Alireza Rabi et al.
JHLT Open
Transplantation: Methods and Outcomes
article

Impact of initial hematocrit levels during direct procurement and perfusion on the likelihood of primary graft dysfunction in donation after circulatory death heart transplantation

Esther Odekunle, George Olverson, Ioannis Mastoris, S. Alireza Rabi, Kamila Drezek, Adham Makarem, E. Michel, Shannon N. Tessier, Asishana A. Osho, David D’Alessandro
article en

Abstract

Higher perfusate HCT was not associated with reduced PGD and may be linked to increased postoperative support requirements. These findings raise important questions about optimal HCT levels for ex vivo perfusion and warrant further prospective investigation.

JHLT OpenVol. 11
Rutgers, The State University of New Jersey (US), Shriners Hospitals for Children - Erie (US), Harvard University (US), Massachusetts General Hospital (US), Shriners Hospitals for Children - Boston (US), Rutgers New Jersey Medical School (US), University of Rochester (US)
Openalex Percentile: Top 46%
Transplantation: Methods and Outcomes
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Impact of initial hematocrit levels during direct procurement and perfusion on the likelihood of primary graft dysfunction in donation after circulatory death heart transplantation — Esther Odekunle, George Olverson, et al. · JHLT Open (2025) | TGRS Research Map | TGRS