Analytical Imprecision and Therapeutic Intervals for Lithium – Are There Implications for Old Age Patients with Bipolar Disorder?
Routine colorimetric methods used for lithium measurements have adequate precision and detection capabilities in the therapeutic windows recommended by the ISBD task force. In addition, the proposed therapeutic intervals are verifiable by real-world patient data.
Authors
- Rajeevan Selvaratnam (ORCID: https://orcid.org/0000-0003-4457-616X)
- Janet R. Zhou (ORCID: https://orcid.org/0000-0002-7137-9674)
- Dionysios Tsoukalas
- Saranya Arnoldo (ORCID: https://orcid.org/0009-0008-0685-8282)
- Peter A. Kavsak (ORCID: https://orcid.org/0000-0003-4576-4744)
- Jennifer Taher (ORCID: https://orcid.org/0000-0001-9377-968X)
- Lei Fu (ORCID: https://orcid.org/0000-0002-5593-4180)
- Sara A. Love
- Felix Leung (ORCID: https://orcid.org/0000-0001-8166-3794)
- Heather Tysick
- Nethra Chittiprol
- Zahraa Ali-Mohammed
Institutions
- Sunnybrook Health Science Centre (CA)
- University Health Network (CA)
- University of Toronto (CA)
- Scarborough Health Network (CA)
- Lakeridge Health (CA)
- William Osler Health System (CA)
- Sinai Health System (CA)
- Siemens Healthcare (United States) (US)
- McMaster University (CA)
Publication Details
- Journal
- Clinical Biochemistry
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.clinbiochem.2025.111057
- Primary Topic
- Bipolar Disorder and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00