Solid Pseudopapillary Neoplasm of the Pancreas Misdiagnosed as Ovarian Torsion in the Second Trimester of Pregnancy

Solid pseudopapillary neoplasm (SPN) of the pancreas is a low-grade malignant tumor affecting young women. Presentation during pregnancy is extremely rare and poses unique diagnostic and management challenges. We present a case of a 23-year-old primigravida at 25 weeks of gestation with recurrent epigastric pain and vomiting. Initial imaging suggested an adnexal mass, raising concerns about ovarian torsion. However, further assessment with MRI revealed a large heterogeneous mass anterior to the left kidney and near the pancreas. Diagnostic laparotomy confirmed a 15 cm mesenteric mass that was completely resected. Histopathological and immunohistochemical evaluations confirmed that the SPN originated in the pancreas. The patient recovered uneventfully and gave birth to a healthy, full-term infant. This case highlights the importance of SPN in the differential diagnosis of abdominal masses during pregnancy and illustrates the safety of second-trimester surgical management.

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Journal
Cureus
Published
2025-11-20
DOI
https://doi.org/10.7759/cureus.97306
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
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article

Solid Pseudopapillary Neoplasm of the Pancreas Misdiagnosed as Ovarian Torsion in the Second Trimester of Pregnancy

Sultan F. Alanesi, Fizan Abdullah, Sawsan Abdel Rahim, Muwahhid Rasheed et al.
Cureus
Pancreatic and Hepatic Oncology Research
article

Solid Pseudopapillary Neoplasm of the Pancreas Misdiagnosed as Ovarian Torsion in the Second Trimester of Pregnancy

Sultan F. Alanesi, Fizan Abdullah, Sawsan Abdel Rahim, Muwahhid Rasheed, Hassan Bahre
article en

Abstract

Solid pseudopapillary neoplasm (SPN) of the pancreas is a low-grade malignant tumor affecting young women. Presentation during pregnancy is extremely rare and poses unique diagnostic and management challenges. We present a case of a 23-year-old primigravida at 25 weeks of gestation with recurrent epigastric pain and vomiting. Initial imaging suggested an adnexal mass, raising concerns about ovarian torsion. However, further assessment with MRI revealed a large heterogeneous mass anterior to the left kidney and near the pancreas. Diagnostic laparotomy confirmed a 15 cm mesenteric mass that was completely resected. Histopathological and immunohistochemical evaluations confirmed that the SPN originated in the pancreas. The patient recovered uneventfully and gave birth to a healthy, full-term infant. This case highlights the importance of SPN in the differential diagnosis of abdominal masses during pregnancy and illustrates the safety of second-trimester surgical management.

CureusVol. 17(11)
Aga Khan Hospital, Kisumu (KE), University of Sharjah (AE)
Openalex Percentile: Top 52%
Pancreatic and Hepatic Oncology Research
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Solid Pseudopapillary Neoplasm of the Pancreas Misdiagnosed as Ovarian Torsion in the Second Trimester of Pregnancy — Sultan F. Alanesi, Fizan Abdullah, et al. · Cureus (2025) | TGRS Research Map | TGRS