Prognostic Significance of HMGA1 in Hepatocellular Carcinoma: Implications for Tumor Progression and Targeted Therapy

HMGA1 serves as a robust prognostic biomarker and functional driver of malignant progression in LIHC. Its integration into prognostic models may enhance risk stratification and guide personalized therapeutic strategies. Nevertheless, further <i>in-vivo</i> validation and prospective clinical studies are required to establish its translational applicability.

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Publication Details

Journal
Archives of Iranian Medicine
Published
2025-10-01
DOI
https://doi.org/10.34172/aim.34456
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Prognostic Significance of HMGA1 in Hepatocellular Carcinoma: Implications for Tumor Progression and Targeted Therapy

Puhua Zeng, Huiying Jian, Tianhao Tong, Zhuo Liu et al.
Archives of Iranian Medicine
Ferroptosis and cancer prognosis
article

Prognostic Significance of HMGA1 in Hepatocellular Carcinoma: Implications for Tumor Progression and Targeted Therapy

Puhua Zeng, Huiying Jian, Tianhao Tong, Zhuo Liu, Jingting Zhang, Wenhui Gao, Renyi Yang, Bin Cheng
article en

Abstract

HMGA1 serves as a robust prognostic biomarker and functional driver of malignant progression in LIHC. Its integration into prognostic models may enhance risk stratification and guide personalized therapeutic strategies. Nevertheless, further <i>in-vivo</i> validation and prospective clinical studies are required to establish its translational applicability.

Archives of Iranian MedicineVol. 28(10)
Hunan University of Traditional Chinese Medicine (CN), Hunan Academy of Traditional Chinese Medicine (CN), Xiangyang Hospital of Traditional Chinese Medicine (CN)
Openalex Percentile: Top 49%
Ferroptosis and cancer prognosis
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