Inhibition of PTTG1 suppresses proliferation and promotes differentiation of neuroblastoma cells by inducing autophagy
PTTG1 is highly expressed in various NB cells. Interfering with PTTG1 induces autophagy, thereby inhibiting SK-N-SH cell proliferation and promoting differentiation.
Authors
- Kanglin Dai
- Lihua Yuan
- Xiaobo Wang (ORCID: https://orcid.org/0000-0003-3594-0679)
- Kenneth Kak Yuen Wong (ORCID: https://orcid.org/0000-0001-7371-503X)
Institutions
- Sun Yat-sen University (CN)
- Queen Mary Hospital (CN)
- The Seventh Affiliated Hospital of Sun Yat-sen University (CN)
- University of Hong Kong - Shenzhen Hospital (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- Pediatric Surgery International
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1007/s00383-025-06246-w
- Primary Topic
- Neuroblastoma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00