Exploring the role of 338 cerebrospinal fluid metabolites in primary brain malignancies risk: a Mendelian randomization study
The findings provide evidence consistent with potential causal associations between ten CSF metabolites and primary brain malignancies, helping us to further understand the pathogenesis of primary brain malignancies and provide clues for the prediction of the disease.
Authors
- Hengqiu He
- Zaicheng Xu (ORCID: https://orcid.org/0000-0002-2870-1365)
- Xue Wu (ORCID: https://orcid.org/0000-0002-2607-8717)
- Zhenzhou Yang (ORCID: https://orcid.org/0000-0003-2496-1992)
- Rui Liao (ORCID: https://orcid.org/0000-0002-0057-2792)
- Yuan Peng (ORCID: https://orcid.org/0000-0001-9563-9568)
- Rong Kong (ORCID: https://orcid.org/0000-0002-2685-9943)
- Xiaoyue Zhang (ORCID: https://orcid.org/0000-0002-5691-3795)
- Fanghao Cai (ORCID: https://orcid.org/0000-0002-6566-5527)
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1007/s12672-025-04111-9
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00