Tetramethoxyluteolin, an active constituent in mulberry leaves, promotes osteogenesis of jaw bone marrow mesenchymal stem cells in periodontitis microenvironment via NF-κB inhibition
TML reduces periodontal inflammation and enhances the osteogenic potential of JBMMSCs by inhibiting the NF-κB pathway, providing a novel strategy for periodontitis-related bone regeneration.
Authors
- Zeyu Wu (ORCID: https://orcid.org/0000-0002-4634-0663)
- Jin Zhao (ORCID: https://orcid.org/0000-0002-5207-4680)
- Yu-ning Xia
- Chao Shan
Institutions
- Xinjiang Medical University (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
Publication Details
- Journal
- Archives of Oral Biology
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.archoralbio.2025.106459
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00