Coronary vasospasms and other cardiac manifestations in Eosinophilic Granulomatosis with Polyangiitis: Clinical impact and frequency in a monocentre study of 103 patients
Cardiac involvement is a common initial manifestation of EGPA and is associated with elevated systemic disease activity. In addition to pericarditis and myocarditis, coronary vasospasms were identified as a rare and severe manifestation of EGPA that may mimic myocardial infarction. Consequently, at the early stage of disease, patients may present with advanced cardiac impairment, emphasising the necessity of prompt diagnostic and therapeutic intervention to positively affect prognosis.
Authors
- Markus A. Schramm (ORCID: https://orcid.org/0000-0003-3513-3842)
- Nils Venhoff (ORCID: https://orcid.org/0000-0001-7729-2759)
- Reinhard Voll (ORCID: https://orcid.org/0000-0002-5542-9133)
- Björn C. Frye (ORCID: https://orcid.org/0000-0003-3520-1868)
- Jens Thiel (ORCID: https://orcid.org/0000-0001-7582-1514)
- Dawid L. Staudacher (ORCID: https://orcid.org/0000-0002-9423-9682)
- Franz Thiele (ORCID: https://orcid.org/0000-0001-6689-8827)
- Christopher L. Schlett (ORCID: https://orcid.org/0000-0002-1576-1481)
Institutions
- University of Freiburg (DE)
- University Medical Center Freiburg (DE)
Publication Details
- Journal
- RMD Open
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1136/rmdopen-2025-005816
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Albert-Ludwigs-Universität Freiburg