Sex specific responses to oral vs. subcutaneous semaglutide in type 2 diabetes mellitus: A 12-month real-world study
This real-world study suggests that subcutaneous semaglutide provides greater metabolic benefits than the oral formulation, particularly in men. Women treated with subcutaneous semaglutide experience more favorable liver responses, emphasizing the personalization of T2D treatment.
Authors
- Laura Maniscalco (ORCID: https://orcid.org/0000-0001-7974-3963)
- Martina Barone (ORCID: https://orcid.org/0000-0003-3356-9861)
- Giorgio Arnaldi (ORCID: https://orcid.org/0000-0002-6204-3423)
- Valentina Guarnotta (ORCID: https://orcid.org/0000-0002-8088-4947)
- Enrica Vigneri
- Felicia Pantò
- Laura Tomasello (ORCID: https://orcid.org/0000-0002-2304-6007)
- Alessandra Piccione
- Maria Bonsangue
- Mariagrazia Irene Mineo
Institutions
- Department of Health (ES)
- Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo (IT)
- University of Palermo (IT)
Publication Details
- Journal
- Nutrition Metabolism and Cardiovascular Diseases
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.numecd.2025.104462
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00