Efficacy and safety of rivaroxaban in neonatal catheter-related thrombosis: a single-center retrospective study of 122 cases
Retrospective data suggest that rivaroxaban is safe and effective in treating neonatal catheter-related thrombosis, with a higher complete thrombus resolution rate observed at 3 months compared to 6 weeks of anticoagulation therapy. Chemotherapy and difficult catheter placement were identified as independent risk factors affecting treatment efficacy. These findings, derived from a single-center retrospective study, require validation through multi-center, prospective, randomized controlled trials.
Authors
- Bin Yang (ORCID: https://orcid.org/0000-0002-7155-6079)
- Yunfeng Lin (ORCID: https://orcid.org/0000-0003-1224-6561)
- Teng Hui Zhan
- Gang Chen (ORCID: https://orcid.org/0000-0002-9989-2381)
- Rong Zhang (ORCID: https://orcid.org/0000-0002-0003-2200)
- Weifeng Cai
Institutions
- Fujian Medical University (CN)
- Fudan University (CN)
- Fujian Women and Children Hospital (CN)
- Education Department of Fujian Province (CN)
- Zhongshan Hospital of Xiamen University (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2025-11-20
- DOI
- https://doi.org/10.7717/peerj.20375
- Primary Topic
- Blood Coagulation and Thrombosis Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fujian Medical University