Hepatocellular carcinoma with pharyngeal metastasis: A case report and literature review

Hepatocellular carcinoma (HCC) is a common and aggressive malignancy. While common metastatic sites of hepatocellular carcinoma include the lung, bone, and lymph nodes, pharyngeal metastasis is extremely rare. This case report presents a unique case of a patient with hepatocellular carcinoma who developed pharyngeal metastasis. We describe the patient's clinical course, diagnostic work-up, and treatment strategies and details. We paid special attention to diagnostic difficulties and to ways of its resolving. Additionally, a comprehensive literature review was performed to summarize the characteristics, possible mechanisms, and management of hepatocellular carcinoma pharyngeal metastasis. By presenting this case and reviewing the literature, we aim to raise awareness among clinicians about this rare metastatic manifestation of hepatocellular carcinoma and provide insights into its diagnosis and treatment.

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Publication Details

Journal
SAGE Open Medical Case Reports
Published
2025-11-01
DOI
https://doi.org/10.1177/2050313x251395984
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
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article

Hepatocellular carcinoma with pharyngeal metastasis: A case report and literature review

Wenchao Zhao, Lijun Zhou, Tan Deng, Qiang Chen
SAGE Open Medical Case Reports
Hepatocellular Carcinoma Treatment and Prognosis
article

Hepatocellular carcinoma with pharyngeal metastasis: A case report and literature review

Wenchao Zhao, Lijun Zhou, Tan Deng, Qiang Chen
article en

Abstract

Hepatocellular carcinoma (HCC) is a common and aggressive malignancy. While common metastatic sites of hepatocellular carcinoma include the lung, bone, and lymph nodes, pharyngeal metastasis is extremely rare. This case report presents a unique case of a patient with hepatocellular carcinoma who developed pharyngeal metastasis. We describe the patient's clinical course, diagnostic work-up, and treatment strategies and details. We paid special attention to diagnostic difficulties and to ways of its resolving. Additionally, a comprehensive literature review was performed to summarize the characteristics, possible mechanisms, and management of hepatocellular carcinoma pharyngeal metastasis. By presenting this case and reviewing the literature, we aim to raise awareness among clinicians about this rare metastatic manifestation of hepatocellular carcinoma and provide insights into its diagnosis and treatment.

SAGE Open Medical Case ReportsVol. 13
Hunan Normal University (CN), Hunan Cancer Hospital (CN), Hunan Provincial People's Hospital (CN), Education Department of Hunan Province (CN)
Openalex Percentile: Top 54%
Hepatocellular Carcinoma Treatment and Prognosis
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