Differential Performance of Polygenic Score for Coronary Artery Disease Based on Coronary Artery Calcium Between Men Living With and Without HIV
The application of a PRS<sub>CAD</sub> to CAC showed lower performance for PLWH than PWOH men. Further research is needed to develop accurate risk prediction models with clinical utility in all patients.
Authors
- Sabina Haberlen (ORCID: https://orcid.org/0000-0002-9467-3454)
- Marios Arvanitis (ORCID: https://orcid.org/0000-0001-8046-6123)
- Jared W. Magnani (ORCID: https://orcid.org/0000-0002-5075-3604)
- Genevieve L. Wojcik (ORCID: https://orcid.org/0000-0001-7206-8088)
- Matthew J. Feinstein
- Wendy S. Post (ORCID: https://orcid.org/0000-0002-8655-5204)
- Matthew Jay Budoff (ORCID: https://orcid.org/0000-0002-9616-1946)
- Steven M. Wolinsky (ORCID: https://orcid.org/0000-0002-9625-6697)
- Priya Duggal (ORCID: https://orcid.org/0000-0001-5809-2081)
- Hee Jin Kim (ORCID: https://orcid.org/0000-0002-0128-2789)
- Eun‐Young Kim (ORCID: https://orcid.org/0000-0002-7436-7396)
- Joseph B. Margolick (ORCID: https://orcid.org/0000-0002-4398-8851)
- Kireem Nam
Institutions
- Northwestern University (US)
- Johns Hopkins University (US)
- University of Pittsburgh (US)
- Johns Hopkins Medicine (US)
- Northwestern University (PH)
- Northwestern Medicine (US)
- Harbor–UCLA Medical Center (US)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1161/jaha.125.045144
- Primary Topic
- HIV-related health complications and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00