Brain iron distribution in transdiagnostic mental health burden
Our finding of a characteristic brain iron distribution pattern in individuals diagnosed with BD, BPD, and ADHD and offspring of diagnosed individuals supports that brain iron patterns may serve as neurobiological correlates for psychiatric disorders conceptualized as spectrum conditions. Further, longitudinal studies are needed to confirm whether pattern analysis of brain iron distribution may represent a transdiagnostic biomarker for a better understanding of underlying neuropathology in psychiatric disorders.
Authors
- Nader Ali Perroud (ORCID: https://orcid.org/0000-0002-9282-9216)
- Paul Gerson Unschuld (ORCID: https://orcid.org/0000-0002-6116-3386)
- Camille Piguet (ORCID: https://orcid.org/0000-0003-4317-0918)
- Sonja M. Kagerer (ORCID: https://orcid.org/0000-0002-9244-4842)
- Rebecca C. Coray (ORCID: https://orcid.org/0000-0001-7775-6859)
- Jatta Berberat (ORCID: https://orcid.org/0000-0002-6551-8308)
- Lopez Julian Gaviria
Institutions
- University of Geneva (CH)
- University Hospital of Zurich (CH)
- Kantonsspital Aarau (CH)
- Vrije Universiteit Amsterdam (NL)
Publication Details
- Journal
- Psychiatry and Clinical Neurosciences Reports
- Published
- 2025-11-19
- DOI
- https://doi.org/10.1002/pcn5.70243
- Primary Topic
- Attention Deficit Hyperactivity Disorder
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Université de Genève
- National Center of Competence in Research Chemical Biology