Executive summary. Screening, staging and follow-up of type 1 diabetes in preclinical stages: consensus of the scientific societies SED, SEEN and SEEP

Type 1 diabetes (T1DM) is an autoimmune disease whose late diagnosis can lead to serious complications such as diabetic ketoacidosis, especially in children. The presence of specific autoantibodies allows for the identification of a presymptomatic phase, opening the door to screening strategies targeting populations at high genetic risk, such as first-degree relatives. This document presents the consensus recommendations of the Spanish Diabetes Society (SED), the Spanish Society of Endocrinology and Nutrition (SEEN) and the Spanish Society of Paediatric Endocrinology (SEEP) on the screening, staging and monitoring of T1DM in preclinical stages. Early identification of the disease will enable a personalised approach to be established, promote health education and, eventually, consider therapeutic interventions that may delay progression to the symptomatic phase. This consensus seeks to establish a common framework for clinical action based on the available evidence, with clear recommendations for its proper implementation.

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Publication Details

Journal
Anales de Pediatría (English Edition)
Published
2025-11-01
DOI
https://doi.org/10.1016/j.anpede.2025.503944
Primary Topic
Diabetes and associated disorders
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article
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article

Executive summary. Screening, staging and follow-up of type 1 diabetes in preclinical stages: consensus of the scientific societies SED, SEEN and SEEP

Virginia Bellido, Ignacio Conget, Dı́dac Mauricio, Isabel Leiva‐Gea et al.
Anales de Pediatría (English Edition)
Diabetes and associated disorders
article

Executive summary. Screening, staging and follow-up of type 1 diabetes in preclinical stages: consensus of the scientific societies SED, SEEN and SEEP

Virginia Bellido, Ignacio Conget, Dı́dac Mauricio, Isabel Leiva‐Gea, Roque Cardona‐Hernandez, Alberto Fernández, María Asunción Martínez-Brocca, Luis Castaño, A. Gila
article en

Abstract

Type 1 diabetes (T1DM) is an autoimmune disease whose late diagnosis can lead to serious complications such as diabetic ketoacidosis, especially in children. The presence of specific autoantibodies allows for the identification of a presymptomatic phase, opening the door to screening strategies targeting populations at high genetic risk, such as first-degree relatives. This document presents the consensus recommendations of the Spanish Diabetes Society (SED), the Spanish Society of Endocrinology and Nutrition (SEEN) and the Spanish Society of Paediatric Endocrinology (SEEP) on the screening, staging and monitoring of T1DM in preclinical stages. Early identification of the disease will enable a personalised approach to be established, promote health education and, eventually, consider therapeutic interventions that may delay progression to the symptomatic phase. This consensus seeks to establish a common framework for clinical action based on the available evidence, with clear recommendations for its proper implementation.

Anales de Pediatría (English Edition)Vol. 103(5)
Hospital Sant Joan de Déu Barcelona (ES), BioCruces Health research Institute (ES), Hospital Universitario Virgen Macarena (ES), Sociedad Española de Endocrinología y Nutrición (ES), Instituto de Biomedicina de Sevilla (ES), Hospital Universitario Virgen del Rocío (ES), Instituto de Investigación Biomédica de Málaga (ES)
Openalex Percentile: Top 63%
Diabetes and associated disorders
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