A retrospective study of the incidence of cancer and associated risk factors in kidney transplant patients in a Latin American population between 2007 and 2022

In a Latin American kidney transplant cohort the incidence of post-transplant malignancy was found to be 14% in a median follow-up of 7 years. This study found that risk factors include age, history of cancer prior to transplantation, and diabetes mellitus. Use of mTOR pathway inhibitors was associated with a reduced risk of solid organ neoplasms. No increase in the frequency of PTLD was found in patients receiving costimulation signal inhibitors.

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Journal
SAGE Open Medicine
Published
2025-11-01
DOI
https://doi.org/10.1177/20503121251387972
Primary Topic
Viral-associated cancers and disorders
Type
article
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article

A retrospective study of the incidence of cancer and associated risk factors in kidney transplant patients in a Latin American population between 2007 and 2022

Maricely Reina, O Olivares, Camilo Montero, Carlos Rosselli San Martín et al.
SAGE Open Medicine
Viral-associated cancers and disorders
article

A retrospective study of the incidence of cancer and associated risk factors in kidney transplant patients in a Latin American population between 2007 and 2022

Maricely Reina, O Olivares, Camilo Montero, Carlos Rosselli San Martín, Rodolfo Torres, David Andrade Fonseca, José López Menéndez, Erick Mendoza, Camilo Ruano
article en

Abstract

In a Latin American kidney transplant cohort the incidence of post-transplant malignancy was found to be 14% in a median follow-up of 7 years. This study found that risk factors include age, history of cancer prior to transplantation, and diabetes mellitus. Use of mTOR pathway inhibitors was associated with a reduced risk of solid organ neoplasms. No increase in the frequency of PTLD was found in patients receiving costimulation signal inhibitors.

SAGE Open MedicineVol. 13
Clínica Santa María (CO), Fundación Universitaria de Ciencias de la Salud (CO), Hospital Universitario Infantil San José (CO), Fundación Universitaria Sanitas (CO)
Openalex Percentile: Top 52%
Viral-associated cancers and disorders
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