Biomarkers influence kidney function estimates more so than race among persons with HIV
Among PWH, cystatin C shifted estimates of kidney function towards normal and resulted in shifts in kidney function categorization much more so than the race effect. As some antiretrovirals raise creatinine without affecting GFR, cystatin C is an important biomarker to confirm diminished kidney function among persons with HIV.
Authors
- Richard A. Teran (ORCID: https://orcid.org/0000-0002-1733-1119)
- Bruce A. Luxon
- Amanda B. Spence (ORCID: https://orcid.org/0000-0001-9011-8456)
- Peggy-ita Obeng-Nyarkoh (ORCID: https://orcid.org/0009-0001-6685-985X)
- Jason G. Umans (ORCID: https://orcid.org/0000-0002-2746-3350)
- Seble Kassaye (ORCID: https://orcid.org/0000-0002-7527-7384)
- Princy Kumar (ORCID: https://orcid.org/0000-0002-5994-2727)
- Christopher A. Loffredo (ORCID: https://orcid.org/0000-0002-3134-6894)
- Joseph Timpone
Institutions
- Georgetown University (US)
- MedStar Health (US)
Publication Details
- Journal
- AIDS Research and Therapy
- Published
- 2025-11-19
- DOI
- https://doi.org/10.1186/s12981-025-00812-x
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00