Pharmacokinetics of mycophenolic acid in plasma and peripheral blood mononuclear cells and its relationship with activity of inosine monophosphate dehydrogenase in Chinese adult kidney allograft recipients
Measurement of MPA concentration and IMPDH activity in PBMCs serves as a complementary method to routine clinical therapeutic drug monitoring, which provide basis for the individual therapy of MPA in Chinese kidney allograft recipients.
Authors
- Hao‐Qiang Shi
- Ying Lu (ORCID: https://orcid.org/0000-0002-3545-1026)
- Bing Chen (ORCID: https://orcid.org/0000-0003-4909-4792)
- Xiaoling Lu (ORCID: https://orcid.org/0000-0002-1151-562X)
- Huimin An
- Kun Shao (ORCID: https://orcid.org/0000-0003-4116-4477)
- Jia‐Qian Lu
- Peijun Zhou (ORCID: https://orcid.org/0000-0002-3498-5317)
Institutions
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-11-19
- DOI
- https://doi.org/10.3389/fphar.2025.1712932
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China