Diagnostic accuracy of GFAP and UCH-L1 for intracranial hemorrhage in blunt head trauma: a prospective study
GFAP and UCH-L1 are highly sensitive and specific biomarkers for early ICH detection in blunt head trauma. Their combined use may enhance triage accuracy, reduce unnecessary imaging, and support rapid clinical decision-making in emergency settings. Larger multicenter studies are warranted to validate these findings and standardize cut-off values.
Authors
- Yasin Bilgin
- Murat Günay (ORCID: https://orcid.org/0000-0002-2079-6654)
- Yusuf Kantar (ORCID: https://orcid.org/0000-0001-8358-5312)
- Uğur Durmuş (ORCID: https://orcid.org/0000-0001-5824-8592)
- Serhat Hayme (ORCID: https://orcid.org/0000-0001-9428-3002)
- Fatih Sarı (ORCID: https://orcid.org/0000-0002-4818-8562)
Institutions
- Erzincan Binali Yıldırım University (TR)
Publication Details
- Journal
- BMC Emergency Medicine
- Published
- 2025-11-19
- DOI
- https://doi.org/10.1186/s12873-025-01398-3
- Citations
- 1
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 1.39