Global phosphoproteome analysis identifies PeVYV P4-induced host protein phosphorylation changes that facilitate viral proliferation
Our findings demonstrate that PeVYV P4-mediated phosphorylation modifications in N. tabacum are crucial for viral infection. This discovery of viral manipulation of host phosphorylation networks provides novel insights into the molecular mechanisms underlying PeVYV pathogenesis, and potential targets for developing PeVYV-resistant cultivars through molecular breeding approaches. These results significantly advance our understanding of the evolutionary arms race between plants and PeVYV at the post-translational modification level.
Authors
- Xiao Yan Yang (ORCID: https://orcid.org/0009-0009-6059-6081)
- Zhanhong Zhang
- X. Lei (ORCID: https://orcid.org/0000-0003-0636-8677)
- Yong Liu (ORCID: https://orcid.org/0000-0001-6932-583X)
- Yali Xu (ORCID: https://orcid.org/0000-0001-6610-8936)
- Xi Ye
- Shijun Li (ORCID: https://orcid.org/0000-0002-4677-6301)
- Xiangwen Luo
- Songbai Zhang (ORCID: https://orcid.org/0000-0001-8883-4525)
- Yueyue Chen
- Yu Zhang (ORCID: https://orcid.org/0000-0002-6552-7642)
- Hui Liu (ORCID: https://orcid.org/0009-0002-8999-9393)
- Ouyang Xian
Institutions
- Huntsman (United States) (US)
- Hunan University (CN)
- Changsha University (CN)
- Hunan Academy of Agricultural Sciences (CN)
- National Engineering Research Center for Information Technology in Agriculture (CN)
- Hunan Agricultural University (CN)
Publication Details
- Journal
- BMC Plant Biology
- Published
- 2025-11-19
- DOI
- https://doi.org/10.1186/s12870-025-07668-3
- Primary Topic
- Plant Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China