Identification of Chondroitin Polymerizing Factor as a Biomarker for Colorectal Cancer by the Human Villi Development Model
These findings validate that villi development can serve as a research model for tumorigenesis, and identify <i>CHPF</i> is an independent oncogenic factor in CRC, suggesting its potential as a prognostic biomarker and a therapeutic target for clinical treatment.
Authors
- Shujun Cheng (ORCID: https://orcid.org/0000-0001-5672-8461)
- Hongxia Li (ORCID: https://orcid.org/0000-0002-1440-1345)
- Wenbin Li (ORCID: https://orcid.org/0000-0001-7638-4395)
- Bo‐Tao Zhang (ORCID: https://orcid.org/0000-0003-0299-8575)
- Lin Feng (ORCID: https://orcid.org/0000-0003-0951-713X)
- Yuanjing Wang (ORCID: https://orcid.org/0000-0003-1972-4634)
- Rongfang Shen
Institutions
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Beijing Tian Tan Hospital (CN)
- Beijing Shijitan Hospital (CN)
- Beijing Obstetrics and Gynecology Hospital (CN)
Publication Details
- Journal
- Cancer Innovation
- Published
- 2025-11-19
- DOI
- https://doi.org/10.1002/cai2.70036
- Primary Topic
- Proteoglycans and glycosaminoglycans research
- Type
- article
- Field-Weighted Citation Impact
- 0.00