Epigenetic alterations in obstructive sleep Apnea: a pooled analysis of DNA methylation profiles in humans and animal models
These findings provide further evidence that epigenetic mechanisms, particularly DNA methylation, mediate the systemic effects of OSA and IH. Our study underscores the need for targeted research to elucidate the causal role of these epigenetic changes and their potential reversibility through therapeutic interventions.
Authors
- Alex Gileles‐Hillel (ORCID: https://orcid.org/0000-0002-0656-905X)
- Eden Engal (ORCID: https://orcid.org/0000-0002-4353-6521)
Institutions
- Hebrew University of Jerusalem (IL)
- Hadassah Medical Center (IL)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2025-11-19
- DOI
- https://doi.org/10.1186/s13148-025-02009-5
- Citations
- 1
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 1.16