Gastrointestinal symptoms in adults with Fabry disease and their associations with physical and mental health
The high frequency of gastrointestinal symptoms in adults with Fabry disease suggests routine gastrointestinal screening alongside pain monitoring in clinical practice. These symptoms were related to disease severity, physical quality of life, and pain. Abdominal pain was most common, while IBS-like symptoms, bloating and nausea also occurred more often than in the general population. Further research on symptom progression and diet is needed.
Authors
- Kristin Ørstavik (ORCID: https://orcid.org/0000-0001-7900-7093)
- Olga Solberg
- Hege Pihlstrøm (ORCID: https://orcid.org/0000-0002-9192-6356)
- Birgitte Berentsen (ORCID: https://orcid.org/0000-0003-3574-7078)
- Trond Jenssen (ORCID: https://orcid.org/0000-0001-6602-8274)
- Sólrún Sigurðardóttir (ORCID: https://orcid.org/0000-0002-7194-3570)
- M.S. Weedon-Fekjær
- Birgitte Bjerkely
- Ketil Heimdal (ORCID: https://orcid.org/0000-0002-8911-3508)
- Harald Weedon‐Fekjær (ORCID: https://orcid.org/0000-0002-9109-0034)
- Jan Gunnar Hatlebakk
Institutions
- Oslo University Hospital (NO)
- University of Oslo (NO)
- Haukeland University Hospital (NO)
- University of Bergen (NO)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-11-19
- DOI
- https://doi.org/10.1186/s12876-025-04439-0
- Primary Topic
- Lysosomal Storage Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00