The diagnostic value of miR-340-5p in pediatric ulcerative colitis and its molecular mechanism by targeting MAP3K2 to modulate intestinal epithelial cell dysfunction
miR-340-5p may serve as a diagnostic biomarker for pediatric UC and exerts its effects by targeting MAP3K2 to regulate cell apoptosis, inflammatory responses, and oxidative stress.
Authors
- Lingxia Ge
- Na Guan
- Fancheng Meng (ORCID: https://orcid.org/0000-0003-0330-2023)
- Xiao Han (ORCID: https://orcid.org/0000-0002-0544-4351)
Institutions
- Qingdao University (CN)
- Nanjing Children's Hospital (CN)
- Third Affiliated Hospital of Guangzhou Medical University (CN)
- Key Laboratory of Guangdong Province (CN)
- Gansu Provincial Hospital (CN)
- Affiliated Hospital of Qingdao University (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Pingliang People's Hospital (CN)
- Nanjing Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Hereditas
- Published
- 2025-11-19
- DOI
- https://doi.org/10.1186/s41065-025-00597-z
- Citations
- 1
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 1.82