Luminescent nanomaterials for photodynamic therapy of glioma

Tumors are difficult to treat due to their complex biological characteristics and resistance to traditionaltreatment methods. Photodynamic therapy (PDT), as an emerging treatment method, has gradually becomea research hotspot for treating tumors, and has received widespread attention due to its targeting andminimal side effects. However, some current photodynamic therapies stil have some shortcomings, such asweak tissue penetration ability of light, low tumor targeting ability of photosensitizers, and hypoxia in thetumor microenvironment. The emergence of self luminous nanomaterials provides new ideas for PDT, as theycan not only serve as effective photosensitizers but also achieve multifunctionality, such as drug carriers andbiological imaging.

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Publication Details

Journal
Photodiagnosis and Photodynamic Therapy
Published
2025-11-01
DOI
https://doi.org/10.1016/j.pdpdt.2025.104866
Primary Topic
Nanoplatforms for cancer theranostics
Type
article
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article

Luminescent nanomaterials for photodynamic therapy of glioma

Yun Niu
Photodiagnosis and Photodynamic Therapy
Nanoplatforms for cancer theranostics
article

Luminescent nanomaterials for photodynamic therapy of glioma

Yun Niu
article en

Abstract

Tumors are difficult to treat due to their complex biological characteristics and resistance to traditionaltreatment methods. Photodynamic therapy (PDT), as an emerging treatment method, has gradually becomea research hotspot for treating tumors, and has received widespread attention due to its targeting andminimal side effects. However, some current photodynamic therapies stil have some shortcomings, such asweak tissue penetration ability of light, low tumor targeting ability of photosensitizers, and hypoxia in thetumor microenvironment. The emergence of self luminous nanomaterials provides new ideas for PDT, as theycan not only serve as effective photosensitizers but also achieve multifunctionality, such as drug carriers andbiological imaging.

Photodiagnosis and Photodynamic TherapyVol. 56
Zhejiang Provincial People's Hospital (CN)
Openalex Percentile: Top 66%
Nanoplatforms for cancer theranostics
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Luminescent nanomaterials for photodynamic therapy of glioma — Yun Niu · Photodiagnosis and Photodynamic Therapy (2025) | TGRS Research Map | TGRS