Retrospective analysis of Hemoporin-mediated photodynamic therapy in the treatment of naive port wine plaques in young patients

To compare the influence factors of Hemoporfin-PDT on the midface, peripheral face and neck of young patients with port-wine stains (PWS). We retrospectively analyzed young patients with PWS who received Hemoporfin-PDT at our center between August 2017 and July 2024. The difference of treatment times and influencing factors were analyzed when the midface, peripheral face and neck reached 75% curative effect. Midface and perifacial face purple PWS require more treatments on average than red PWS to achieve a 75% response rate. However, this difference was not observed in the neck. Regardless of treatment history, the average number of treatments required to achieve 75% efficacy was nearly identical for the midface, perifacial face, and neck. In the midface and peripheral face, patients with the purple type required a higher mean number of treatment sessions compared to those with the red type. Previous treatment history was not a factor.