Photodynamic diagnosis-guided treatment of Erythroplasia of Queyrat with ALA-PDT: A case report

Queyrat erythroplasia (EQ) is a rare form of squamous cell carcinoma (SCC) in situ, commonly found on the glans, penis, and coronary sulcus, and clinically presenting as one or more well-marginated erythematous velvety plaques. EQ can transform into invasive SCC and requires early diagnosis and treatment. Photodynamic diagnosis (PDD) is a fluorescence imaging technique that can be used for a wide range of non-pigmented skin tumours, helping us to diagnose skin tumours and monitor efficacy. Here, we report a case of EQ successfully treated with 5-aminolevulinic acid photodynamic therapy (ALA-PDT) assisted by PDD technology, suggesting that PDD technology has a role in the treatment and diagnosis of patients with EQ.

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Publication Details

Journal
Photodiagnosis and Photodynamic Therapy
Published
2025-11-01
DOI
https://doi.org/10.1016/j.pdpdt.2025.104855
Primary Topic
Nonmelanoma Skin Cancer Studies
Type
article
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article

Photodynamic diagnosis-guided treatment of Erythroplasia of Queyrat with ALA-PDT: A case report

Xiang Nong, Di Zhang, Shang‐Zhong Xu, L. Nie
Photodiagnosis and Photodynamic Therapy
Nonmelanoma Skin Cancer Studies
article

Photodynamic diagnosis-guided treatment of Erythroplasia of Queyrat with ALA-PDT: A case report

Xiang Nong, Di Zhang, Shang‐Zhong Xu, L. Nie
article en

Abstract

Queyrat erythroplasia (EQ) is a rare form of squamous cell carcinoma (SCC) in situ, commonly found on the glans, penis, and coronary sulcus, and clinically presenting as one or more well-marginated erythematous velvety plaques. EQ can transform into invasive SCC and requires early diagnosis and treatment. Photodynamic diagnosis (PDD) is a fluorescence imaging technique that can be used for a wide range of non-pigmented skin tumours, helping us to diagnose skin tumours and monitor efficacy. Here, we report a case of EQ successfully treated with 5-aminolevulinic acid photodynamic therapy (ALA-PDT) assisted by PDD technology, suggesting that PDD technology has a role in the treatment and diagnosis of patients with EQ.

Photodiagnosis and Photodynamic TherapyVol. 56
Kunming Medical University (CN), First Affiliated Hospital of Kunming Medical University (CN)
Openalex Percentile: Top 54%
Nonmelanoma Skin Cancer Studies
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Photodynamic diagnosis-guided treatment of Erythroplasia of Queyrat with ALA-PDT: A case report — Xiang Nong, Di Zhang, et al. · Photodiagnosis and Photodynamic Therapy (2025) | TGRS Research Map | TGRS