Photodynamic Therapy for Perifolliculitis capitis abscedens et suffodiens: A Case Series Demonstrating Long-Term Efficacy

Perifolliculitis capitis abscedens et suffodiens(PCAS) is a challenging chronic inflammatory dermatosis with limited treatment options. This case series explores the efficacy of photodynamic therapy in managing recalcitrant PCAS, providing valuable insights into its long-term benefits. Four young male patients with severe, treatment-resistant PCAS underwent a series of Photodynamic therapy treatments(PDT) using 5-aminolevulinic acid as a photosensitizer and a 635 nm light source. Patients received 4-6 weekly treatments, followed by two-year follow-up. All patients demonstrated significant improvement, including reduced active lesions, inflammation, and hair regrowth. PDT appears to be an effective and well-tolerated treatment for PCAS, offering sustained benefits, including long-term remission and hair regrowth. Further studies are needed to establish optimal treatment protocols.