Photodynamic Therapy Combined with Localized Sclerotherapy Successfully Treated Perineal Hemangioma

Perineal hemangioma is a rare and challenging vascular tumor due to its sensitive location and potential complications, such as ulceration and infection. This case highlights the successful treatment of a perineal hemangioma in a 5-year-old child using combined photodynamic therapy (PDT) and localized sclerotherapy. The patient underwent three sessions of PDT, with noticeable improvement observed after the third session. Localized sclerotherapy was then performed, resulting in partial improvement. One month later, the lesion worsening prompted two additional PDT sessions, leading to significant progress and complete lesion resolution. The combination of localized sclerotherapy and PDT led to a significant reduction in lesion color and normalization of surrounding skin. No recurrence was observed during a three-month follow-up period. PDT, combined with localized sclerotherapy, provides a promising approach for managing perineal hemangiomas, warranting further investigation and case reporting.

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Publication Details

Journal
Photodiagnosis and Photodynamic Therapy
Published
2025-11-01
DOI
https://doi.org/10.1016/j.pdpdt.2025.104904
Primary Topic
Vascular Malformations and Hemangiomas
Type
article
Field-Weighted Citation Impact
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article

Photodynamic Therapy Combined with Localized Sclerotherapy Successfully Treated Perineal Hemangioma

Kang Zeng, Sijin He, Xiao-wen Huang, Yue Zheng et al.
Photodiagnosis and Photodynamic Therapy
Vascular Malformations and Hemangiomas
article

Photodynamic Therapy Combined with Localized Sclerotherapy Successfully Treated Perineal Hemangioma

Kang Zeng, Sijin He, Xiao-wen Huang, Yue Zheng, Siqi Zheng
article en

Abstract

Perineal hemangioma is a rare and challenging vascular tumor due to its sensitive location and potential complications, such as ulceration and infection. This case highlights the successful treatment of a perineal hemangioma in a 5-year-old child using combined photodynamic therapy (PDT) and localized sclerotherapy. The patient underwent three sessions of PDT, with noticeable improvement observed after the third session. Localized sclerotherapy was then performed, resulting in partial improvement. One month later, the lesion worsening prompted two additional PDT sessions, leading to significant progress and complete lesion resolution. The combination of localized sclerotherapy and PDT led to a significant reduction in lesion color and normalization of surrounding skin. No recurrence was observed during a three-month follow-up period. PDT, combined with localized sclerotherapy, provides a promising approach for managing perineal hemangiomas, warranting further investigation and case reporting.

Photodiagnosis and Photodynamic TherapyVol. 56
Nanfang Hospital (CN), Southern Medical University (CN)
Openalex Percentile: Top 46%
Vascular Malformations and Hemangiomas
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