Photodynamic Therapy Combined with Localized Sclerotherapy Successfully Treated Perineal Hemangioma
Perineal hemangioma is a rare and challenging vascular tumor due to its sensitive location and potential complications, such as ulceration and infection. This case highlights the successful treatment of a perineal hemangioma in a 5-year-old child using combined photodynamic therapy (PDT) and localized sclerotherapy. The patient underwent three sessions of PDT, with noticeable improvement observed after the third session. Localized sclerotherapy was then performed, resulting in partial improvement. One month later, the lesion worsening prompted two additional PDT sessions, leading to significant progress and complete lesion resolution. The combination of localized sclerotherapy and PDT led to a significant reduction in lesion color and normalization of surrounding skin. No recurrence was observed during a three-month follow-up period. PDT, combined with localized sclerotherapy, provides a promising approach for managing perineal hemangiomas, warranting further investigation and case reporting.
Authors
- Kang Zeng (ORCID: https://orcid.org/0000-0003-0131-2690)
- Sijin He
- Xiao-wen Huang (ORCID: https://orcid.org/0000-0001-8288-1427)
- Yue Zheng
- Siqi Zheng (ORCID: https://orcid.org/0009-0009-8094-0417)
Institutions
- Nanfang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Photodiagnosis and Photodynamic Therapy
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1016/j.pdpdt.2025.104904
- Primary Topic
- Vascular Malformations and Hemangiomas
- Type
- article
- Field-Weighted Citation Impact
- 0.00