Topical 5-aminolevulinic acid photodynamic therapy for recalcitrant cutaneous warts in children

This article reports a retrospective study evaluating the efficacy and safety of 20% aminolevulinic acid photodynamic therapy (ALA-PDT) in the treatment of recalcitrant warts in children. The study included 7 patients with recalcitrant warts (including 2 cases of single perithyroid warts, 3 cases of multiple perithyroid warts, 2 cases of plantar warts) who received ALA-PDT treatment. Among them, 6 patients had complete clearance of skin lesions, with an effective treatment rate of 85.7%. After 12 weeks of follow-up after treatment, all patients with completely cleared skin lesions did not experience disease recurrence. The adverse reactions of ALA-PDT include pain, swelling, blisters, etc., and all patients have good tolerance to adverse reactions. Research has confirmed that 20% ALA-PDT is safe and effective in treating recalcitrant warts in children, and is worth promoting in clinical practice.