Clinical Observation of Pyogenic Granuloma Treated with Combined Long-Pulse 1064nm Nd:YAG Laser and Pulsed CO2 Laser Photodynamic Therapy

To explore the clinical efficacy and safety of long-pulse 1064nm Nd:YAG laser combined with pulsed CO2 laser and topical application of aminolevulinic acid hydrochloride for photodynamic therapy in the treatment of pyogenic granuloma. 20 patients with pyogenic granuloma were treated with a combination of long-pulse 1064nm Nd:YAG laser and pulsed CO2 laser along with photodynamic therapy using aminolevulinic acid hydrochloride. The efficacy, recurrence rate, and safety were observed at 1 month and 2 months post-treatment. All patients achieved a 100%cure rate and total effectiveness with a single treatment, with no infections, ulcers, or scars observed. Eight patients experienced mild pigmentation, which gradually resolved within one month, and there were no recurrences. The combined therapy of long-pulse 1064nm Nd:YAG laser and pulsed CO2 laser with photodynamic therapy is highly effective in treating pyogenic granuloma, with no recurrences and minimal adverse reactions, significantly improving patient satisfaction.