The Synergistic Effects of Photodynamic Therapy and Immunotherapy in the Treatment of Skin Cancer

This study investigates the synergistic effects of photodynamic therapy (PDT) combined with immunotherapy in the treatment of skin cancer. By reviewing current clinical and experimental data, the study analyzes the underlying mechanisms, advantages, and challenges of combining PDT with immunotherapy. The findings suggest that PDT enhances the efficacy of immunotherapy by activating the immune system through localized photosensitizing reactions, which in turn strengthens the tumor immune response. The combination therapy overcomes the limitations of monotherapies, demonstrating superior therapeutic potential and anti-tumor effects. This paper provides novel insights into the combined application of PDT and immunotherapy and offers valuable references for developing clinical treatment strategies for skin cancer.

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Publication Details

Journal
Photodiagnosis and Photodynamic Therapy
Published
2025-11-01
DOI
https://doi.org/10.1016/j.pdpdt.2025.104871
Primary Topic
Photodynamic Therapy Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

The Synergistic Effects of Photodynamic Therapy and Immunotherapy in the Treatment of Skin Cancer

Wei Cui
Photodiagnosis and Photodynamic Therapy
Photodynamic Therapy Research Studies
article

The Synergistic Effects of Photodynamic Therapy and Immunotherapy in the Treatment of Skin Cancer

Wei Cui
article en

Abstract

This study investigates the synergistic effects of photodynamic therapy (PDT) combined with immunotherapy in the treatment of skin cancer. By reviewing current clinical and experimental data, the study analyzes the underlying mechanisms, advantages, and challenges of combining PDT with immunotherapy. The findings suggest that PDT enhances the efficacy of immunotherapy by activating the immune system through localized photosensitizing reactions, which in turn strengthens the tumor immune response. The combination therapy overcomes the limitations of monotherapies, demonstrating superior therapeutic potential and anti-tumor effects. This paper provides novel insights into the combined application of PDT and immunotherapy and offers valuable references for developing clinical treatment strategies for skin cancer.

Photodiagnosis and Photodynamic TherapyVol. 56
Gansu Provincial Hospital (CN)
Openalex Percentile: Top 50%
Photodynamic Therapy Research Studies
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