A case report of photodynamic therapy-assisted surgical treatment of recurrent oral squamous cell carcinoma
To report the efficacy of photodynamic therapy-assisted surgical treatment of recurrent oral squamous cell carcinoma. A 71-year-old patient with left cheek squamous cell carcinoma had two recurrences in 3 years. Oral examination showed granular nodules on the surface of the left lower gingival buccal groove. The biopsy pathological diagnosis was "recurrence of left cheek squamous cell carcinomaafter surgery". Five photodynamic therapy sessions were conducted, during the period of waiting for surgical resection was performed. Postoperative pathological report: (left cheek) Severe dysplasia were showed in squamous epithelium on the surface of some areas, tending to local early canceration. The histological depth of infiltration (DOI) was about 1mm. No obvious recurrence was found in the follow-up. Preoperative photodynamic therapy for oral squamous cell carcinoma can effectively control or reduce the lesion range, thereby reducing the extent of surgical resection and avoiding greater surgical trauma such as skin grafting.
Authors
- Xinyi Ni
- Hongwei Liu (ORCID: https://orcid.org/0000-0002-0285-1664)
- Lei Zhang (ORCID: https://orcid.org/0000-0002-9832-952X)
- Ying Han (ORCID: https://orcid.org/0000-0001-8131-7971)
Institutions
- King University (US)
- Peking University (CN)
Publication Details
- Journal
- Photodiagnosis and Photodynamic Therapy
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1016/j.pdpdt.2025.104970
- Primary Topic
- Photodynamic Therapy Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00