A case report of photodynamic therapy-assisted surgical treatment of recurrent oral squamous cell carcinoma

To report the efficacy of photodynamic therapy-assisted surgical treatment of recurrent oral squamous cell carcinoma. A 71-year-old patient with left cheek squamous cell carcinoma had two recurrences in 3 years. Oral examination showed granular nodules on the surface of the left lower gingival buccal groove. The biopsy pathological diagnosis was "recurrence of left cheek squamous cell carcinomaafter surgery". Five photodynamic therapy sessions were conducted, during the period of waiting for surgical resection was performed. Postoperative pathological report: (left cheek) Severe dysplasia were showed in squamous epithelium on the surface of some areas, tending to local early canceration. The histological depth of infiltration (DOI) was about 1mm. No obvious recurrence was found in the follow-up. Preoperative photodynamic therapy for oral squamous cell carcinoma can effectively control or reduce the lesion range, thereby reducing the extent of surgical resection and avoiding greater surgical trauma such as skin grafting.

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Publication Details

Journal
Photodiagnosis and Photodynamic Therapy
Published
2025-11-01
DOI
https://doi.org/10.1016/j.pdpdt.2025.104970
Primary Topic
Photodynamic Therapy Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

A case report of photodynamic therapy-assisted surgical treatment of recurrent oral squamous cell carcinoma

Xinyi Ni, Hongwei Liu, Lei Zhang, Ying Han
Photodiagnosis and Photodynamic Therapy
Photodynamic Therapy Research Studies
article

A case report of photodynamic therapy-assisted surgical treatment of recurrent oral squamous cell carcinoma

Xinyi Ni, Hongwei Liu, Lei Zhang, Ying Han
article en

Abstract

To report the efficacy of photodynamic therapy-assisted surgical treatment of recurrent oral squamous cell carcinoma. A 71-year-old patient with left cheek squamous cell carcinoma had two recurrences in 3 years. Oral examination showed granular nodules on the surface of the left lower gingival buccal groove. The biopsy pathological diagnosis was "recurrence of left cheek squamous cell carcinomaafter surgery". Five photodynamic therapy sessions were conducted, during the period of waiting for surgical resection was performed. Postoperative pathological report: (left cheek) Severe dysplasia were showed in squamous epithelium on the surface of some areas, tending to local early canceration. The histological depth of infiltration (DOI) was about 1mm. No obvious recurrence was found in the follow-up. Preoperative photodynamic therapy for oral squamous cell carcinoma can effectively control or reduce the lesion range, thereby reducing the extent of surgical resection and avoiding greater surgical trauma such as skin grafting.

Photodiagnosis and Photodynamic TherapyVol. 56
King University (US), Peking University (CN)
Openalex Percentile: Top 50%
Photodynamic Therapy Research Studies
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