Applications of reflectance confocal microscopy in follow-up of actinic keratosis after 5-aminolevulinic acid photodynamic therapy

To determine the application value of reflectance confocal microscopy in follow-up of actinic keratosis after 5 - aminolevulinic acid photodynamic therapy. RCM scanning was per_x0002_formed in 16 patients with actinic keratosis at 1 month, 3 months and 6 months after 5 -aminolevulinic acid photodynamic therapy. Histological examination was performed in patients with tumor tissue found by RCM. RCM regular reexamination was performed in 16 patients, tumor cells were found in 1 case at 1 month after therapy, and tumor cells were found in 2 cases at 3 months after therapy. All 3 patients were diagnosed with actinic keratosis by histological examination again. No tumor cells were found in the other 13 patients after follow-up for 6 months. RCM has important application value in follow-up of actinic keratosis after photodynamic therapy.