Clinical Study on the Treatment of Glioblastoma Patients with Sonodynamic Therapy Combined with Radiotherapy and Chemotherapy
Glioblastoma, has poor prognosis. Sonodynamic therapy (SDT) offers a new non-invasive treatment approach. This clinical trial assesses SDT combined with radiotherapy and chemotherapy. Among 19 patients, 68.4% showed stable disease and 15.8% achieved partial remission at six months. Median progression-free survival was 7.6 months, and overall survival was 9.47 months. SDT combined with radiotherapy and chemotherapy shows promise in treating glioblastoma, improving survival and symptoms.
Authors
- T. Liu (ORCID: https://orcid.org/0009-0003-0718-0614)
- Boya Zha (ORCID: https://orcid.org/0000-0003-3006-1608)
- Linkuan Huangfu
- Haiyang Cui
- Yingjuan Zheng (ORCID: https://orcid.org/0000-0002-6515-8998)
- Pengcheng Zhou (ORCID: https://orcid.org/0000-0003-1477-0586)
- Peihong Li
- Xiaohao Liu (ORCID: https://orcid.org/0009-0002-8516-5017)
- Miaomiao Zhang (ORCID: https://orcid.org/0000-0001-7517-2382)
- Zhifei Dai
Institutions
- Peking University (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
- Capital Normal University (CN)
Publication Details
- Journal
- Photodiagnosis and Photodynamic Therapy
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1016/j.pdpdt.2025.104954
- Primary Topic
- Ultrasound and Hyperthermia Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00