CO2 laser combined with photodynamic therapy for the treatment of recalcitrant plantar warts

Plantar warts are a common clinical condition caused by human papillomavirus infection, and are more likely to occur in individuals with a history of trauma or weakened immune systems. Patients with a long history of the disease may experience pain while walking or standing, and the skin lesions may gradually increase in number and size. Clinical diagnosis is relatively straightforward, Common treatment methods include laser therapy, cryotherapy, surgical excision, and medication. However, high recurrence rates and significant trauma remain challenges in clinical treatment. In this case, the patient had a long history of the disease and had undergone stomach cancer surgery a year prior, with multiple treatments attempted without satisfactory results. We employed carbon dioxide laser therapy in combination with photodynamic therapy, which yielded good results, and there has been no recurrence after six months of follow-up treatment.

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Publication Details

Journal
Photodiagnosis and Photodynamic Therapy
Published
2025-11-01
DOI
https://doi.org/10.1016/j.pdpdt.2025.104873
Primary Topic
Nonmelanoma Skin Cancer Studies
Type
article
Field-Weighted Citation Impact
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article

CO2 laser combined with photodynamic therapy for the treatment of recalcitrant plantar warts

Zhixia Fan, Guoying Miao, Xin Wang, Panpan Suo
Photodiagnosis and Photodynamic Therapy
Nonmelanoma Skin Cancer Studies
article

CO2 laser combined with photodynamic therapy for the treatment of recalcitrant plantar warts

Zhixia Fan, Guoying Miao, Xin Wang, Panpan Suo
article en

Abstract

Plantar warts are a common clinical condition caused by human papillomavirus infection, and are more likely to occur in individuals with a history of trauma or weakened immune systems. Patients with a long history of the disease may experience pain while walking or standing, and the skin lesions may gradually increase in number and size. Clinical diagnosis is relatively straightforward, Common treatment methods include laser therapy, cryotherapy, surgical excision, and medication. However, high recurrence rates and significant trauma remain challenges in clinical treatment. In this case, the patient had a long history of the disease and had undergone stomach cancer surgery a year prior, with multiple treatments attempted without satisfactory results. We employed carbon dioxide laser therapy in combination with photodynamic therapy, which yielded good results, and there has been no recurrence after six months of follow-up treatment.

Photodiagnosis and Photodynamic TherapyVol. 56
Affiliated Hospital of Hebei University (CN)
Openalex Percentile: Top 54%
Nonmelanoma Skin Cancer Studies
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CO2 laser combined with photodynamic therapy for the treatment of recalcitrant plantar warts — Zhixia Fan, Guoying Miao, et al. · Photodiagnosis and Photodynamic Therapy (2025) | TGRS Research Map | TGRS