Observation on the Efficacy of Surgery Combined with Photodynamic Therapy for Vulvar cancer

To observe the efficacy and safety of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) combined with surgical treatment for vulvar cancer . Method: A total of 20 cases of female patients with vulvar skin cancer treated with 5-aminolevulinic acid photodynamic therapy (ALA-PDT) combined with surgery in our hospital from 2020 to 2024 were collected. The clinical efficacy, healing status, cosmetic effect, complications, and recurrence were observed through follow-up. 19 cases have shown no recurrence so far, and 1 case recurred due to involvement of lymph nodes at the time of admission. The wound healing was good, the function of the urethral orifice and the appearance of the vaginal orifice were well preserved, and complications were few. ALA-PDT combined with surgical treatment for vulvar non-metastatic cancer has definite efficacy, high healing rate, good cosmetic effect, and can reduce the incidence of complications and recurrence rate, making it safe and reliable.