Topical Imiquimod Induces Facial Dermatitis After Treating Common Warts: A Case Report

This case report describes a 41-year-old male who developed dermatitis reactions following treatment with 5% imiquimod cream for facial common warts. After undergoing local cryotherapy, the patient applied imiquimod cream every other day. Three days later, erythema, erosion, and crusting appeared in the treated area. After treatment was discontinued, the erosion gradually healed; however, two weeks later, erythematous scaling accompanied by itching emerged. Dermatological examination revealed scattered papules and scaling, with dermatoscopic findings indicating an inflammatory response. Although imiquimod is considered safe and effective for treating common warts, this case suggests that it may induce dermatitis. The report emphasizes the need to consider individual variability and potential side effects when using imiquimod for treatment.

Authors

Publication Details

Journal
Photodiagnosis and Photodynamic Therapy
Published
2025-11-01
DOI
https://doi.org/10.1016/j.pdpdt.2025.105141
Primary Topic
Nonmelanoma Skin Cancer Studies
Type
article
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article

Topical Imiquimod Induces Facial Dermatitis After Treating Common Warts: A Case Report

Zhen Liang, J. Han
Photodiagnosis and Photodynamic Therapy
Nonmelanoma Skin Cancer Studies
article

Topical Imiquimod Induces Facial Dermatitis After Treating Common Warts: A Case Report

Zhen Liang, J. Han
article en

Abstract

This case report describes a 41-year-old male who developed dermatitis reactions following treatment with 5% imiquimod cream for facial common warts. After undergoing local cryotherapy, the patient applied imiquimod cream every other day. Three days later, erythema, erosion, and crusting appeared in the treated area. After treatment was discontinued, the erosion gradually healed; however, two weeks later, erythematous scaling accompanied by itching emerged. Dermatological examination revealed scattered papules and scaling, with dermatoscopic findings indicating an inflammatory response. Although imiquimod is considered safe and effective for treating common warts, this case suggests that it may induce dermatitis. The report emphasizes the need to consider individual variability and potential side effects when using imiquimod for treatment.

Photodiagnosis and Photodynamic TherapyVol. 56
Openalex Percentile: Top 54%
Nonmelanoma Skin Cancer Studies
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