Curative Effect Observation of Photodynamic Therapy Combined with phlebotomy in a Patient with Panfacial Actinic Keratosis

to explore the therapeutic efficacy of photodynamic therapy combined with bloodletting in a patient with panfacial actinic keratosis. Based on the lesion conditions, quick pricking and scattered needing methods were employed for treatment. The treatment was administered once a week, with four sessions constituting one therapeutic course. The therapeutic outcomes were observed. After phlebotomy pre-treatment, PDT was performed. This approach enhanced the transdermal absorption of the photosensitizer in the lesions, reduced local ecchymosis, accelerated the shedding of scabs, and yielded definite therapeutic effects. Follow-up over six months revealed no recurrence. The combination of PDT and phlebotomy in the treatment of AK is effective in improving clinical outcomes and shortening the recovery period. This method is worth promoting.

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Publication Details

Journal
Photodiagnosis and Photodynamic Therapy
Published
2025-11-01
DOI
https://doi.org/10.1016/j.pdpdt.2025.105085
Primary Topic
Nonmelanoma Skin Cancer Studies
Type
article
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article

Curative Effect Observation of Photodynamic Therapy Combined with phlebotomy in a Patient with Panfacial Actinic Keratosis

Mary Sun
Photodiagnosis and Photodynamic Therapy
Nonmelanoma Skin Cancer Studies
article

Curative Effect Observation of Photodynamic Therapy Combined with phlebotomy in a Patient with Panfacial Actinic Keratosis

Mary Sun
article en

Abstract

to explore the therapeutic efficacy of photodynamic therapy combined with bloodletting in a patient with panfacial actinic keratosis. Based on the lesion conditions, quick pricking and scattered needing methods were employed for treatment. The treatment was administered once a week, with four sessions constituting one therapeutic course. The therapeutic outcomes were observed. After phlebotomy pre-treatment, PDT was performed. This approach enhanced the transdermal absorption of the photosensitizer in the lesions, reduced local ecchymosis, accelerated the shedding of scabs, and yielded definite therapeutic effects. Follow-up over six months revealed no recurrence. The combination of PDT and phlebotomy in the treatment of AK is effective in improving clinical outcomes and shortening the recovery period. This method is worth promoting.

Photodiagnosis and Photodynamic TherapyVol. 56
Wuhan No.1 Hospital (CN), Wuhan No.9 Hospital (CN)
Openalex Percentile: Top 54%
Nonmelanoma Skin Cancer Studies
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Curative Effect Observation of Photodynamic Therapy Combined with phlebotomy in a Patient with Panfacial Actinic Keratosis — Mary Sun · Photodiagnosis and Photodynamic Therapy (2025) | TGRS Research Map | TGRS